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IVF Implantation Failure Clinic
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Michael A. Feinman, MD, FACOG
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HYSTEROSALPINGOGRAM (x-ray dye test or HSG)

Most infertility patients in the U.S. have had this test done as part of their initial evaluation.  Many overseas patients have not, and some American women have not.  This test is important because it looks both at the uterus and the tubes.  A combined laparoscopy/hysteroscopy, though more invasive is a suitable substitute for this test.  Abnormalities of the uterus, such as polyps, fibroids, scar tissue, and septums can interfere with implantation or cause miscarriages.  All of these conditions should be corrected before undergoing IVF.  In addition, if the tubes are blocked at their far ends (Hydrosalpinx), many studies have shown this condition to decrease IVF success rates by 50%.  When these blocked tubes are found, they need to be surgically removed.

HYSTEROSCOPY

If an HSG was done in the past, hysteroscopy is useful to find new problems like polyps or small septums that have been ignored.  Hysteroscopy can be done as an office procedure or with light anesthesia. 

SPERM DNA FRAGMENTATION

A number of tests have been developed that evaluate the integrity sperm DNA.  The most popular version is called the DNA fragmentation assay.  It evaluates the integrity of DNA in the sperm.  If this is abnormally  high, the evidence shows that this will result in lower fertilization rates, lower implantation rates, and higher miscarriage rates.  Men with normal semen analysis results can have abnormal DNA results.  If an abnormal result is obtained, a urological consultation may be appropriate.  If no physical abnormalities are found, various approaches have been tried to improve the DNA quality.

ENDOMETRIAL BIOPSY TESTS FOR IMPLANTATION MARKERS

Over the past 25 years, a variety of tests have been developed that help determine if the endometrium (uterine lining) is receptive to implantation.  The older tests, while backed by scientific articles, do not generally  guide the physician as to how the problem can be improved.  A “third- generation” version called the Endometrial Receptive Assay (ERA) uses more current gene expression technology to see if the endometrial “implantation window” is open on the correct day of the cycle.  If it is not, this can be manipulated by freezing embryos and transferring them in a protocol that adjusts the number of days of progesterone given prior to the transfer.

Our experience with this assay confirms their finding that about 1 in 5 infertile women have an endometrial implantation problem, and changing the number of days of progesterone has helped many women with prior failed cycles finally conceive.

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Email feinmanivf@havingbabies.com TODAY!


 

Fertility Treatments that Work

Here, failure is not an option! For those of you who have tried again and again but all treatments to this point have failed, the IVF Implantation Failure Clinic is here to change all that. Contact Dr. Michael Feinman and learn about how he can assist you with making your dream family come true. 

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IVF Implantation Failure Clinic
1220 La Venta Drive Suite 103
Westlake Village, CA 91361
feinmanivf@havingbabies.com
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IVF Implantation Failure Clinic-Hope is Here

Here, failure is not an option! For those of you who have tried again and again but all treatments to this point have failed, the IVF Implantation Failure Clinic is here to change all that. Contact Dr. Michael Feinman and learn about how he can assist you with making your dream family come true.